Veröffentlichungen

Christoph Bobeth, Kees Kleihues-van Tol, Martin Rößler, Veronika Bierbaum, Michael Gerken, Christian Günster, Patrik Dröge, Thomas Ruhnke, Monika Klinkhammer-Schalke, Jochen Schmitt1, Olaf Schoffer

Erfolg des Datenlinkage von GKV-Daten und Daten klinischer Krebsregister im Rahmen des WiZen-Projekts

Anke Reinacher-Schick; Celine Lugnier; Pompiliu Piso; Emmannouil Fokas; Matthias Ebert; Tanja; Zimmermann; Ulrich Wedding; Anna-Lena Kraeft; Olaf Schoffer; Sabine Sommerlatte; Thomas Birkner; Sarah Förster; Stefan Rolf Benz; Monika Klinkhammer-Schalke; Wolfgang Knauf; Ralf-Dieter Hofheinz; Andrea Tannapfel; Jochen Schmitt; Bernhard Wörmann ; Jan Schildmann

S1 Guideline for prioritization in gastrointestinal cancer care – scarcity of resources in the pandemic context

Braun R, Klinkhammer-Schalke M, Zeissig SR, Kleihus van Tol K, Bolm L, Honselmann KC, Petrova E, Lapshyn H, Deichmann S, Abdalla TSA, Heckelmann B, Bronsert P, Zemskov S, Hummel R, Keck T, Wellner UF.

Clinical Outcome and Prognostic Factors of Pancreatic Adenosquamous Carcinoma Compared to Ductal Adenocarcinoma-Results from the German Cancer Registry Group.

Cancers (Basel). 2022 Aug 16;14(16):3946. doi: 10.3390/cancers14163946.

PMID: 36010939 Free PMC article.

Acs M, Gerken M, Gajic I, Mayr M, Zustin J, Piso P.
Ten-year single-center experience with treatment of primary diffuse malignant peritoneal mesothelioma (DMPM) by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Langenbecks Arch Surg. 2022 Jun 23. doi: 10.1007/s00423-022-02594-6. Online ahead of print. PMID: 35732846

Roessler M, Schmitt J, Bobeth C, Gerken M, Kleihues-van Tol K, Reissfelder C, Rau BM, Distler M, Piso P, Günster C, Klinkhammer-Schalke M, Schoffer O, Bierbaum V.
Is treatment in certified cancer centers related to better survival in patients with pancreatic cancer? Evidence from a large German cohort study.
BMC Cancer. 2022 Jun 7;22(1):621. doi: 10.1186/s12885-022-09731-w. PMID: 35672675

5-022-09731-w. PMID: 35672675

Gennari P, Tchaikovski S, Mészáros J, Gerken M, Klinkhammer-Schalke M, Toth G, Ortmann O, Eggemann H, Ignatov A.
Protective effect of pre-operative conization in patients undergoing surgical treatment for early-stage cervical cancer.
Gynecol Oncol. 2022 Jul;166(1):57-60. doi: 10.1016/j.ygyno.2022.05.014. Epub 2022 May 23. PMID: 35618539

Spoerl S, Gerken M, Chamilos C, Spoerl S, Fischer R, Vielsmeier V, Künzel J, Bohr C, Meier JK, Ettl T, Reichert TE, Spanier G.
Clinical significance of panendoscopy in initial staging of oral squamous cell carcinoma and detection of synchronous second malignancies of the upper aerodigestive tract - Insights from a retrospective population-based cohort study.
J Craniomaxillofac Surg. 2022 Jun;50(6):515-522. doi: 10.1016/j.jcms.2022.04.001. Epub 2022 May 2. PMID: 35562318

Fante MA, Felsenstein M, Mayer S, Gerken M, Klinkhammer-Schalke M, Herr W, Vogelhuber M, Reichle A, Heudobler D.
All-Oral Low-Dose Chemotherapy TEPIP is Effective and Well-Tolerated in Relapsed/Refractory Patients With Aggressive B-Cell Lymphoma.
Front Oncol. 2022 May 10;12:852987. doi: 10.3389/fonc.2022.852987. eCollection 2022. PMID: 35619924

Filippini Velázquez G, Schiele S, Gerken M, Neumaier S, Hackl C, Mayr P, Klinkhammer-Schalke M, Illerhaus G, Schlitt HJ, Anthuber M, Kröncke T, Messmann H, Märkl B, Schmid C, Trepel M, Müller G, Claus R, Hackanson B.
Predictive preoperative clinical score for patients with liver-only oligometastatic colorectal cancer.
ESMO Open. 2022 Apr 20;7(3):100470. doi: 10.1016/j.esmoop.2022.100470. Online ahead of print. PMID: 35461024

Deichmann S, Dworschak O, Kulemann B, Höppner J, Bolm L, Klinkhammer-Schalke M, Zeissig SR, Kleihus van Tol K, Braun R, Lapshyn H, Keck T, Wellner UF, Honselmann KC.
Incidence, Treatment and Survival in Pancreatic Cancer- Data of the Nationwide Oncological Quality Conference from a Surgical Perspective.
Zentralbl Chir. 2022 Apr;147(2):147-154. doi: 10.1055/a-1768-1012. Epub 2022 Apr 4. PMID: 35378553

Bolm L, Zemskov S, Zeller M, Baba T, Roldan J, Harrison JM, Petruch N, Sato H, Petrova E, Lapshyn H, Braun R, Honselmann KC, Hummel R, Dronov O, Kirichenko AV, Klinkhammer-Schalke M, Kleihues-van Tol K, Zeissig SR, Rades D, Keck T, Fernandez-Del Castillo C, Wellner UF, Wegner RE.
Concepts and Outcomes of Perioperative Therapy in Stage IA-III Pancreatic Cancer-A Cross-Validation of the National Cancer Database (NCDB) and the German Cancer Registry Group of the Society of German Tumor Centers (GCRG/ADT).
Cancers (Basel). 2022 Feb 9;14(4):868. doi: 10.3390/cancers14040868. PMID: 35205616

Spoerl S, Spoerl S, Reil S, Gerken M, Ludwig N, Taxis J, Fischer R, Ettl T, Reichert TE, Spanier G.
Prognostic Value of Perineural Invasion on Survival and Recurrence in Oral Squamous Cell Carcinoma.
Diagnostics (Basel). 2022 Apr 24;12(5):1062. doi: 10.3390/diagnostics12051062. PMID: 35626218

Röhrmoser K, Ignatov A, Gerken M, Ortmann O, Klinkhammer-Schalke M, Papathemelis T.
Risk factors and temporal patterns of recurrences in patients with vulvar cancer: implications for follow-up intervals and duration.
J Cancer Res Clin Oncol. 2022 Feb 18. doi: 10.1007/s00432-022-03954-x. Online ahead of print. PMID: 35179644

Acs M, Halmy L, Isgandarova S, Blaj S, Gerken M, Hormann B, Piso P.
Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Doxorubicin for 90 Minutes Versus 60 Minutes After Cytoreductive Surgery (CRS). Does the 30-Minute Difference Matter? A Comparative Study in a High Volume Centre.
Anticancer Res. 2022 Feb;42(2):1019-1029. doi: 10.21873/anticanres.15563. PMID: 35093903

P. Hellmund, J. Schmitt, M. Roessler, F. Meier, O. Schoffer
Targeted and Checkpoint Inhibitor Therapy of Metastatic Malignant Melanoma in Germany, 2000–2016

Tobias Robold, Jakob Neumeier, Michael Ried, Reiner Neu, Zsolt Sziklavari, Christian Grosser, Monika Klinkhammer-Schalke, Hans-Stefan Hofmann
Surgical treatment of lung cancer: how has the introduction of the 8th edition of the TNM classification affected guideline-based therapy? [article in German]
Zentralbl Chir. 2020 Dec;145(6):589-596. doi: 10.1055/a-1164-7058. Epub 2020 Jul 6. PMID: 32629508 doi: 10.1055/a-1164-7058

Staubach P, Scharl A, Ignatov A, Ortmann O, Inwald EC, Hildebrandt T, Gerken M, Klinkhammer-Schalke M, Scharl S, Papathemelis T.
Sentinel lymph node detection by means of indocyanine green using the Karl Storz VITOM® fluorescence camera: a comparison between primary sentinel lymph node biopsy versus sentinel lymph node biopsy after neoadjuvant chemotherapy.
J Cancer Res Clin Oncol. 2020 Nov 23. doi: 10.1007/s00432-020-03461-x. Online ahead of print. PMID: 33230583

Spoerl S, Gerken M, Fischer R, Mamilos A, Spoerl S, Wolf S, Pohl F, Klingelhöffer C, Ettl T, Reichert TE, Spanier G.
Lymphatic and vascular invasion in oral squamous cell carcinoma: Implications for recurrence and survival in a population-based cohort study.
Oral Oncol. 2020 Oct 5;111:105009. doi: 10.1016/j.oraloncology.2020.105009. Online ahead of print. PMID: 3303218

Reinert C, Gerken M, Rathberger K, Krueger K, Klinkhammer-Schalke M, Lindberg-Scharf P, Koelbl O, Proescholdt MA, Riemenschneider MJ, Pukrop T, Bumes E, Hutterer M, Hau P.
Single-institution cross-sectional study to evaluate need for information and need for referral to psychooncology care in association with depression in brain tumor patients and their family caregivers.
BMC Psychol. 2020 Sep 10;8(1):96. doi: 10.1186/s40359-020-00460-y. PMID: 32912313

Völkel, V., Draeger, T., Gerken, M., Klinkhammer-Schalke, M., Benz, S., Fürst, A.
Laparoscopic surgery for colon cancer - A systematic review with special focus on real-world data.
coloproctology (2020) 10. September 2020. doi: 10.1007/s00053-020-00481-6

Hellmund P, Schmitt J, Roessler M, Meier F, Schoffer O.
Targeted and Checkpoint Inhibitor Therapy of Metastatic Malignant Melanoma in Germany, 2000-2016.
Cancers (Basel). 2020 Aug 20;12(9):E2354. doi: 10.3390/cancers12092354. PMID: 32825357
Acknowledgement: Cancer Register of Southwest Saxony, Zwickau, Zwickau, Germany; Clinical Cancer Registry Dresden, Dresden, Germany; Clinical Cancer Registry of the Charité Comprehensive Cancer Center, Berlin, Germany; Klinisches Krebsregister Halle, Halle, Germany; Onkologische Qualitätssicherung (QS) in Westfalen-Lippe, Münster, Germany; Tumour Centre Chemnitz, Chemnitz, Germany; Tumour Centre Erfurt, Erfurt, Germany; Tumour Centre Leipzig, Leipzig, Germany; Tumour Centre Oberfranken, Bayreuth, Germany; Tumour Centre Regensburg, Regensburg, Germany; Tumour Centre Ulm/Comprehensive Cancer Centre Ulm (CCCU), Ulm, Germany; Tumour Centre Wiesbaden, Wiesbaden, Germany.

Teufel A, Gerken M, Fürst A, Ebert M, Hohenthanner I, Klinkhammer-Schalke M.
Benefit of adjuvant chemotherapy in high-risk colon cancer: A 17-year population-based analysis of 6131 patients with Union for International Cancer Control stage II T4N0M0 colon cancer.
Eur J Cancer. 2020 Aug 7;137:148-160. doi: 10.1016/j.ejca.2020.06.036. Online ahead of print. PMID: 32777714

Spoerl S, Gerken M, Mamilos A, Fischer R, Wolf S, Nieberle F, Klingelhöffer C, Meier JK, Spoerl S, Ettl T, Reichert TE, Spanier G.
Lymph node ratio as a predictor for outcome in oral squamous cell carcinoma: a multicenter population-based cohort study.
Clin Oral Investig. 2020 Aug 4. doi: 10.1007/s00784-020-03471-6. Online ahead of print. PMID: 32754787

Jansen L, Behrens G, Finke I, Maier W, Gerken M, Pritzkuleit R, Holleczek B, Brenner H; German Cancer Survival Working Group.
Area-Based Socioeconomic Inequalities in Colorectal Cancer Survival in Germany: Investigation Based on Population-Based Clinical Cancer Registration.
Front Oncol. 2020 May 29;10:857. doi: 10.3389/fonc.2020.00857. eCollection 2020. PMID: 32670870

Spanier G, Böttcher J, Gerken M, Fischer R, Roth G, Lehn P, Klingelhöffer C, Meier JK, Fraccaroli A, Tischer J, Ettl T, Klinkhammer-Schalke M, Reichert TE, Spoerl S.
Prognostic value of perioperative red blood cell transfusion and anemia on survival and recurrence in oral squamous cell carcinoma.
Oral Oncol. 2020 May 7;107:104773. doi: 10.1016/j.oraloncology.2020.104773. PMID:32388408

Prantl L, Gerken M, Zeman F, Leitzmann M, Koller M, Klinkhammer-Schalke M, Evert M, Kuehlmann B, Biermann N
Incidence of Anaplastic Large Cell Lymphoma and Breast-Implant-Associated Lymphoma—An Analysis of a Certified Tumor Registry over 17 Years
J. Clin. Med. April, 2020, 9, 1247; doi: 10.3390/jcm9051247

Klinkhammer-Schalke M, Steinger B, Koller M, Zeman F, Fürst A, Gumpp J, Obermaier R, Piso P, Lindberg-Scharf P; Regensburg QoL Study Group.
Diagnosing deficits in quality of life and providing tailored therapeutic options: Results of a randomised trial in 220 patients with colorectal cancer.
Eur J Cancer. 2020 Mar 13;130:102-113. doi: 10.1016/j.ejca.2020.01.025. [Epub ahead of print] PMID:32179445

Papathemelis T, Scharl A, Anapolski M, C Inwald E, Ignatov A, Ortmann O, Gerken M, Klinkhammer-Schalke M, Scharl S.
Value of indocyanine green pelvic lymph node mapping in the surgical approach of cervical cancer.
Arch Gynecol Obstet. 2020 Feb 11. doi: 10.1007/s00404-020-05457-x. [Epub ahead of print] PMID: 32048031

Finke I, Behrens G, Schwettmann L, Gerken M, Pritzkuleit R, Holleczek B, Brenner H, Jansen L; German Cancer Survival Working Group.
Socioeconomic differences and lung cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Lung Cancer. 2020 Feb 4;142:1-8. doi: 10.1016/j.lungcan.2020.01.021. [Epub ahead of print] PMID: 32044589

Schmuck R, Gerken M, Teegen EM, Krebs I, Klinkhammer-Schalke M, Aigner F, Pratschke J, Rau B, Benz S.
Gender comparison of clinical, histopathological, therapeutic and outcome factors in 185,967 colon cancer patients.
Langenbecks Arch Surg. 2020 Jan 31. doi: 10.1007/s00423-019-01850-6. [Epub ahead of print] PMID:32002628

Papathemelis T, Oppermann H, Grafl S, Gerken M, Pauer A, Scharl S, Scharl A, Inwald E, Ignatov A, Ortmann O, Klinkhammer-Schalke M, Hein A, Beckmann MW, Lux MP (2020).
Long-term outcome of patients with intermediate- and high-risk endometrial cancer after pelvic and paraaortic lymph node dissection: a comparison of laparoscopic vs. open procedure.
J Cancer Res Clin Oncol. 2020 Jan 4. doi: 10.1007/s00432-019-03122-8. [Epub ahead of print] PMID: 31901975

Völkel V, Draeger T, Schnitzbauer V, Gerken M, Benz S, Klinkhammer-Schalke M, Fürst A. (2019) Surgical treatment of rectal cancer patients aged 80 years and older-a German nationwide analysis comparing short- and long-term survival after laparoscopic and open tumor resection. Eur J Surg Oncol. 2019 May 9. pii: S0748-7983(19)30443-3. doi:10.1016/j.ejso.2019.05.005. [Epub ahead of print] PMID: 31092363

Voelkel V, Draeger T, Groothuis-Oudshoorn CGM, de Munck L, Hueting T, Gerken M, Klinkhammer-Schalke M, Lavric M, Siesling S. (2019) Predicting the risk of locoregional recurrence after early breast cancer: an external validation of the Dutch INFLUENCE-nomogram with clinical cancer registry data from Germany. J Cancer Res Clin Oncol. 2019 Mar 29. doi: 10.1007/s00432-019-02904-4. [Epub ahead of print] PMID: 30927074

Papathemelis T, Knobloch S, Gerken M, Scharl A, Anapolski M, Ignatov A, Inwald EC, Ortmann O, Scharl S, Klinkhammer-Schalke M. (2019) Impact of nodal status and treatment strategy on overall survival in advanced stage cervical cancer. J Cancer Res Clin Oncol. 2019 Mar 18. doi: 10.1007/s00432-019-02890-7

Draeger T, Völkel V, Schnitzbauer V, Gerken M, Benz S, Klinkhammer-Schalke M, Fürst A. (2019) Laparoscopic and open resection of rectal cancer-is age an effect modifier for short- and long-term survival? Int J Colorectal Dis. 2019 Feb 18. doi: 10.1007/s00384-019-03265-7. [Epub ahead of print] PMID: 30778670

Wimmer T, Ortmann O, Gerken M, Klinkhammer-Schalke M, Koelbl O, Inwald EC. (2019) Adherence to guidelines and benefit of adjuvant radiotherapy in patients with invasive breast cancer: results from a large population-based cohort study of a cancer registry. Arch Gynecol Obstet. 2019 Jan 4. doi.org/10.1007/s00404-018-5030-z [Epub ahead of print] PMID: 30607594

Seliger C, Schaertl J, Gerken M, Luber C, Proescholdt M, Riemenschneider MJ, Leitzmann MF, Hau P, Klinkhammer-Schalke M. (2018) Use of statins or NSAIDs and survival of patients with high-grade glioma.

Int J Colorectal Dis. 2018 Aug 21. PLoS ONE 2018 Dec 13(12): e0207858. doi.org/10.1371/journal

Piso P, Stierstorfer K, Gerken M, Klinkhammer-Schalke M.(2018) Benefit of cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy in patients with isolated peritoneal metastases from colorectal cancer.
Int J Colorectal Dis. 2018 Aug 21. doi.org/10.1007/s00384-018-3146-z [Epub ahead of print] PMID:30132068

Seliger C, Luber C, Gerken M, Schaertl J, Proescholdt M, Riemenschneider MJ, Meier CR, Bogdahn U, Leitzmann MF, Klinkhammer-Schalke M, Hau P. (2018) Use of metformin and survival of patients with high-grade glioma. Int J Cancer. 2018 Aug 9. doi: 10.1002/ijc.31783 [Epub ahead of print] PMID:30091464

Papathemelis T, Hassas D, Gerken M, Klinkhammer-Schalke M, Scharl A, Lux MP, Beckmann MW, Scharl S. (2018) Is there a benefit of lymphadenectomy for overall and recurrence-free survival in type I FIGO IB G1-2 endometrial carcinoma? A retrospective population-based cohort analysis. J Cancer Res Clin Oncol. 2018 Jul 23. doi: 10.1007/s00432-018-2715-4 [Epub ahead of print] PMID: 30039227

Ott C, Gerken M, Hirsch D, Fest P, Fichtner-Feigl S, Munker S, Schnoy E, Stroszczynski C, Vogelhuber M, Herr W, Evert M, Reng M, Schlitt HJ, Klinkhammer-Schalke M, Teufel A. (2018) Advanced Mucinous Colorectal Cancer: Epidemiology, Prognosis and Efficacy of Chemotherapeutic Treatment. Digestion. 2018 Jun 5;98(3):143-152. doi: 10.1159/000487710 PMID: 29870979

Munker S, Gerken M, Fest P, Ott C, Schnoy E, Fichtner-Feigl S, Wiggermann P, Vogelhuber M, Herr W, Stroszczynski C, Schlitt HJ, Evert M, Reng M, Klinkhammer-Schalke M, Teufel A. (2018) Chemotherapy for metastatic colon cancer: No effect on survival when the dose is reduced due to side effects. BMC Cancer. 2018 Apr 23;18(1):455. doi: 10.1186/s12885-018-4380-zPMID: 29685155

Völkel V, Draeger T, Gerken M, Fürst A, Klinkhammer-Schalke M.(2018) Langzeitüberleben von Patienten mit Kolon- und Rektumkarzinomen: Ein Vergleich von Darmkrebszentren und nicht zertifizierten Krankenhäusern - [Long-Term Survival of Patients with Colon and Rectum Carcinomas: Is There a Difference Between Cancer Centers and Non-Certified Hospitals?]. Gesundheitswesen. 2018 Apr 19. doi: 10.1055/a-0591-3827 PMID: 29672814

Draeger T, Völkel V, Gerken M, Klinkhammer-Schalke M, Fürst A (2018). Long-term oncologic outcomes after laparoscopic versus open rectal cancer resection: a high-quality population-based analysis in a Southern German district. Surg Endosc. 2018 Apr 2. doi: 10.1007/s00464-018-6148-6. PMID: 29611044

Völkel V, Draeger T, Gerken M, Klinkhammer-Schalke M, Fürst A (2018). Long-term oncologic outcomes after laparoscopic vs. open colon cancer resection: a high-quality population-based analysis in a Southern German district. Surg Endosc. 2018 Mar 30. doi: 10.1007/s00464-018-6158-4. PMID: 29602999

Reinert C, Rathberger K, Klinkhammer-Schalke M, Kölbl O, Proescholdt M, Riemenschneider MJ, Schuierer G, Hutterer M, Gerken M, Hau P (2018). Information needs and requirements in patients with brain tumours and their relatives. J Neurooncol 2018 Mar 7. doi.org/10.1007/s11060-018-2811-y PMID: 29516343

Liebig-Hörl G, Puchner C, Gerken M, Klinkhammer-Schalke M, Fürst A (2018). Therapeutische Strategie bei Frühkarzinom im Rektum (T1-Karzinom) [Treatment strategy for early stage rectal cancer (T1 carcinoma)]. Chirurg 2018 Feb 14 doi: 10.1007/s00104-018-0603-8  PMID: 29445855

Papathemelis Th, Jablonsky E, Hauzenberger T, Scharl A, Gerken M, Klinkhammer-Schalke M, Hipp M, Scharl S (2018). Sentinel lymph node biopsy (SLNB) in breast cancer patients by means of indocyanine green (ICG) using the Karl Storz VITOM fluorescence camera. BioMed Research International Volume 2018 (2018), doi.org/10.1155/2018/6251468

Scharl S, Papathemelis T, Kronberger K, Gerken M, Scharl A, Kölbl O, Klinkhammer-Schalke M (2018). Does post-operative radiochemotherapy improve survival in high-grade endometrial cancer patients? Results of a population-based cohort analysis of a cancer registry. Arch Gynecol Obstet. 2018 Feb 7. doi: 10.1007/s00404-018-4708-6. [Epub ahead of print]